Thursday, June 18, 2009

World's Deadliest Virus

http://home.wangjianshuo.com/archives/2003/2/12/guangzhou-virus-street.jpg

Nature sure has created some tiny monsters when it comes to microbes—bugs that make us throw up, ooze pus, bleed out of our eyes and cough up blood. But which take top honors (or dishonors) for being the most lethal of all?


HIV/AIDS, the Global Tragedy HIV, the virus that causes AIDS

HIV

AIDS is a pandemic—a disease outbreak that is happening all over the world. In 2000 alone, 3,000,000 people died of AIDS. Since the AIDS pandemic began around 1985, almost 22,000,000 people have died from the disease. Right now, HIV infects more than 36,000,000 people across the world, so that death toll will definitely get a lot bigger over the next several years. HIV doesn’t kill people itself. Instead, the virus shuts down a person’s immune defenses—the tools used to fight off invading germs—by infecting and destroying important immune cells called T cells.

Once a person loses too many T cells, his or her body can no longer deal with other microbes that cause infections. HIV merely opens the floodgates. Eventually HIV-infected people become overrun by germs and die of lung infections, skin infections or other diseases. We now have several drugs that fight HIV. They cannot cure the infection, but they can keep it in check. Unfortunately, victims of HIV have to take several of these drugs every day for life and the drugs are very expensive. In Africa and other developing parts of the world where HIV is spreading most rapidly, most people don’t have enough money to buy these drugs. That’s why we can expect the death toll from HIV/AIDS to get a lot bigger over the next several years. Nature sure has created some tiny monsters when it comes to microbes—bugs that make us throw up, ooze pus, bleed out of our eyes and cough up blood. But which take top honors (or dishonors) for being the most lethal of all?


The Flu Virus—
Even Deadlier than HIV? Influenza A viruses, one of the several types of flu viruses


flu virus

Oh come on now, I’m sure you’re saying. The flu virus here in a list of the most lethal microbes? Sure, every year during what’s called "the flu season" tens of thousands of people get the flu. Despite feeling all achy and lousy for several days, most people eventually beat the virus and recover just fine. But that’s not how it went during the 1918 flu season. That year, World War I was raging so the effects of the flu virus sort of got overshadowed by the bigger, more obvious effects of bullets and bombs. However, in 1918 the flu virus killed at least 675,000 American people. Worldwide, it killed at least 21,000,000 people. These are low estimates. Some research now suggests that the flu may have killed 40,000,000 to 50,000,000 people around the world that year. Researchers still aren’t sure why the 1918 flu virus was so deadly.

Victims of the flu that year died in a gruesome way, the virus causing so much fluid to build up in their lungs so rapidly that it was like drowning. If higher estimates of how many people died from the 1918 flu are true, then the 1918 flu is the deadliest microbe ever in a single year. Thank goodness we haven’t seen a flu bug that deadly again—but will we someday?

The Plague


the plague bacterium

The 1918 flu virus and HIV are the biggest killers of modern times. But back in the 14th century, the bacterium that causes bubonic plague, or the Black Death as it was also known, was the baddest bug of all.

In just a few years, from 1347 to 1351, the plague killed off about 75,000,000 people worldwide, including one-third of the entire population of Europe at that time. It spread through Asia, Italy, North Africa, Spain, Normandy, Switzerland, and eastward into Hungary. After a brief break, it crossed into England, Scotland, and then to Norway, Sweden, Denmark, Iceland and Greenland. Yersinia pestis, the plague bacteria
Courtesy of Neal Chamberlain The plague bacterium is called Yersinia pestis. There are two main forms of the disease. In the bubonic form, the bacteria cause painful swellings as large as an orange to form in the armpits, neck and groin. These swellings, or buboes, often burst open, oozing blood and pus. Blood vessels leak blood that puddles under the skin, giving the skin a blackened look. That’s why the disease became known as the Black Death. At least half of its victims die within a week. The pneumonic form of plague causes victims to sweat heavily and cough up blood that starts filling their lungs. Almost no one survived it during the plague years. Yersinia pestis is the deadliest microbe we’ve ever known, although HIV might catch up to it. Yersinia pestis is still around in the world. Fortunately, with bacteria-killing antibiotics and measures to control the pests—rats and mice—that spread the bacteria, we’ve managed to conquer this killer.

Ebola, the Bloody Virus

Ebola virus

Some of you at the beginning of this page might have thought of the Ebola virus as the scariest, deadliest microbe you’ve ever heard of. Those of you who did so have probably seen the movie Outbreak or read The Hot Zone, which spotlighted this grisly virus.

Ebola virus Courtesy of CDC Ebola is definitely a nasty killer. It is part of a group of viruses that, among other effects on the body, cause the blood to stop clotting. Victims begin oozing blood from their mouths, noses, internal organs, even their eyes. It kills up to almost 90% of those who get infected.

With that kind of death rate, Ebola would be the deadliest microbe of all if it was more common. Fortunately, infections by this virus are pretty rare. There have only been seven outbreaks in humans. It has killed just over 800 people since the first outbreak in the Democratic Republic of the Congo (formerly called Zaire) in 1976. While outbreaks of this virus are rare and relatively small, Ebola is still one mean microbe that I wouldn’t ever want to tangle with.



--

Thursday, May 14, 2009

10 Worst Countries to be a Blogger




“The governments on the list are trying to roll back the information revolution, and, for now, they are having success,” Simon added. “Freedom of expression groups, concerned governments, the online community, and technology companies need to come together to defend the rights of bloggers around the world.”


CPJ issued its report to mark World Press Freedom Day, May 3, and to call attention to online repression, a great emerging threat to press freedom worldwide. CPJ considers bloggers whose work is reportorial or fact-based commentary to be journalists. In 2008, CPJ found, bloggers and other online journalists were the single largest professional group in prison, overtaking print and broadcast journalists for the first time.



10. EGYPT

Egypt a country where more than 100 bloggers were detained last year alone.


Amer is jailed for insulting the president and Islam. (Reuters)
Amer is jailed for insulting the president and Islam. (Reuters)

Authorities block only a small number of Web sites, but they monitor Internet activity on a regular basis. Traffic from all Internet service providers passes through the state-run Egypt Telecom. Authorities regularly detain critical bloggers for open-ended periods. Local press freedom groups documented the detention of more than 100 bloggers in 2008 alone. Although most bloggers were released after short periods, some were held for months and many were kept without judicial order. Most detained bloggers report mistreatment, and a number have been tortured.

Lowlight: Blogger Abdel Karim Suleiman, known online as Karim Amer, is serving a four-year prison term on charges of insulting Islam and Egyptian President Hosni Mubarak.


9. TURKMENISTAN

Turkmenistan, where the nation's first internet cafe was guarded by troops.

President Gurbanguly Berdymukhammedov promised to open his isolated country to the world by providing public Internet access. But when the country’s first Internet café opened in 2007, it was guarded by soldiers, connections were uneven, the hourly fee was prohibitively high, and authorities monitored or blocked access to certain sites. The Russian telecommunications company MTS, which entered the Turkmen market in 2005, started offering Web access from mobile phones in June 2008, but service agreements require customers to avoid Web sites critical of the Turkmen government.

Lowlight: Turkmentelecom, the state Internet service provider, routinely blocks access to dissident and opposition sites, while it monitors e-mail accounts registered with Gmail, Yahoo, and Hotmail.




8. CHINA


With nearly 300 million people online—more than any other country in the world—China has a vibrant digital culture. But Chinese authorities also maintain the world’s most comprehensive online censorship program, one emulated by many other countries. The government relies on service providers to filter searches, block critical Web sites, delete objectionable content, and monitor e-mail traffic. Because China’s traditional press is tightly controlled, bloggers often break news and provide provocative commentary. Blogs, for example, played prominent roles in spreading news and information about the 2008 Sichuan earthquake. But bloggers who go too far in promoting unpopular views or reporting sensitive information can find themselves in jail. At least 24 online writers are now in prison, CPJ research shows.

Lowlight: In 2008, the National Office for Cleaning Up Pornography and Fighting Illegal Publications announced that it had removed more than 200 million “harmful” online items during the prior year.


7. TUNISIA

Internet service providers are required to submit IP addresses and other identifying information to the government on a regular basis. All Internet traffic flows through a central network, allowing the government to filter content and monitor e-mails. The government employs an array of techniques to harass bloggers: conducting surveillance, restricting bloggers’ movements, and undertaking electronic sabotage. Online writers Slim Boukhdhir and Mohamed Abbou have served jail time for their work.

Lowlight: In a March address, President Zine El Abidine Ben Ali warned writers against examining government “mistakes and violations,” saying it was “an activity that is unbecoming of our society and is not an expression of freedom or democracy.”


6. VIETNAM


Bloggers have daringly tried to fill the gap in independent news that is left by the traditional state-controlled media. The government has responded with more regulation. Authorities have called on international technology companies such as Yahoo, Google, and Microsoft to provide information about bloggers who use their platforms. Last September, prominent blogger Nguyen Van Hai, also known as Dieu Cay, was sentenced to 30 months in prison on tax evasion charges. CPJ research shows the charges were in reprisal for his blogging.

Lowlight: In October 2008, the Ministry of Information and Communication created a new agency tasked with monitoring the Internet.


5. SAUDI ARABIA

Saudi Arabia, a country where an estimated 400,00 sites are blocked.

An estimated 400,000 sites are blocked inside the kingdom, including those that tackle political, social, or religious issues. Self-censorship is widespread. Aside from “indecent” material, Saudi Arabia blocks “anything contrary to the state or its system,” a standard that has been interpreted liberally. In 2008, influential clerics called for harsh punishment, including flogging and death, for online writers guilty of posting material deemed heretical.

Lowlight: Blogger Fouad Ahmed al-Farhan was jailed without charge for several months in 2007 and 2008 for promoting reform and the release of political prisoners.


4. CUBA

Cuba, where 21 bloggers are in jail.

Sánchez’s Generación Y is among a small but emerging group of independent Cuban blogs. (CPJ)
Sánchez’s Generación Y is among a small but emerging group of independent Cuban blogs. (CPJ)

Only government officials and people with links to the Communist Party have Web access. The general population goes online at hotels or government-controlled Internet cafés by means of expensive voucher cards. A small number of independent bloggers such as Yoani Sánchez detail everyday life and offer criticism of the regime. Their blogs are hosted outside the country and are largely blocked on the island. Two independent bloggers tell CPJ that they are harassed by authorities. Only pro-government bloggers can post their material on domestic sites that can be easily accessed.

Lowlight: The government now jails 21 writers who were on the leading edge of online journalism in the early part of the decade. These writers, all but one of whom was jailed in 2003, phoned or faxed their material to overseas Web sites for posting.


3. SYRIA


The government uses filtering methods to block politically sensitive sites. Authorities detain bloggers for posting content, even third-party material, deemed to be “false” or detrimental to “national unity.” Self-censorship is pervasive. In 2008, the Ministry of Communications ordered Internet café owners to get identification from all patrons, to record customer names and times of use, and to submit the documentation regularly to authorities. Human rights groups noted that authorities harass and detain bloggers perceived as antigovernment.

Lowlight: Waed al-Mhana, an advocate for endangered archaeological sites, is on trial for a posting that criticized the demolition of a market in Old Damascus.


2. IRAN

Iran, a country where a young blogger died in prison last month, was named as the second-worst country.

Authorities regularly detain or harass bloggers who write critically about religious or political figures, the Islamic revolution, and its symbols. The government requires all bloggers to register their Web sites with the Ministry of Art and Culture. Government officials claim to have blocked millions of Web sites, according to news reports. A newly created special prosecutor’s office specializes in Internet issues and works directly with intelligence services. Pending legislation would make the creation of blogs promoting “corruption, prostitution, and apostasy” punishable by death.

Lowlight: Blogger Omidreza Mirsayafi, jailed for insulting the country’s religious leaders, died in Evin Prison in March under circumstances that have not been fully explained.


1. BURMA

Burma has been judged the worst country in the world for online restrictions in a report looking at the repression faced by bloggers.

Bloggers inside Burma proved invaluable in passing out information during the September 2007 uprisings, leading to the ruling military junta blocking the Internet completely for a period, reports The Guardian.

Zarganar is serving a 59-year prison term. (AP)
Zarganar is serving a 59-year prison term. (AP)

Burma, which heavily censors print and broadcast media, has also applied extensive restrictions on blogging and other Internet activity. Private Internet penetration is very small—only about 1 percent, according to the Internet research group OpenNet Initiative—so most citizens access the Internet in cybercafés. Authorities heavily regulate those cafés, requiring them, for example, to enforce censorship rules. The government, which shut down the Internet altogether during a popular uprising in 2007, has the capability to monitor e-mail and other communication methods and to block users from viewing Web sites of political opposition groups, according to OpenNet Initiative. At least two bloggers are now in prison.

Lowlight: Blogger Maung Thura, popularly known as Zarganar, is serving a 59-year prison term for disseminating video footage after Cyclone Nargis in 2008.



--